Extreme drug resistant tuberculosis (XDR-TB) update

Mycobacterium tuberculosis Multi-drug resistant TB (MDR-TB), is caused by strains of Mycobacterium tuberculosis which are resistant to at least two of the main first-line TB drugs, is already a growing concern. XDR-TB is defined as strains which are resistant to all the current the front-line drugs, but also three or more of the six classes of second-line drugs. In a few rare cases, a strain resistant to all currently available drugs have been seen.
Since WHO tuberculosis experts convened in South Africa last year to discuss how to address the problem, XDR-TB has slowly continued making its way around the world, recently being detected in India where it could account for 8% of those who suffer from TB, although there is no official data on the prevalence of XDR-TB in India and it is nearly impossible to determine the true prevalence of this strain in India.
The latest news is that a U.S. citizen – currently in hospital isolation in Georgia after becoming the first person quarantined in the U.S. by the government for more than 40 years – put air passengers at risk by boarding transatlantic flights knowing he was infected with XDR-TB when he traveled to Europe for his wedding and honeymoon.
Enforced quarantine is likely to become a more frequent choice for health care authorities and governments as XDR-TB continues its inexorable spread.

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