MicrobiologyBytes: Infection & Immunity: Immunodeficiency diseases Updated: October 21, 2004 Search

CLASSIFICATION OF IMMUNODEFICIENCY DISEASES:

PRIMARY IMMUNODEFICIENCIES:
Immune deficiencies affecting B cell function: X-linked agammaglobulinaemia
hypogammaglobulinaemia of infancy
IgA deficiency
IgG subclass deficiency, and selective antibody deficiency with normal immunoglobulins
common variable immune deficiency
Combined T and B cell deficiencies: severe combined immunodeficiency
"Pure" T cell immunodeficiencies: mucocutaneous Candidiasis
X-linked lymphoproliferative syndrome
Primary syndromes which are associated with immunodeficiency: di George anomaly
Wiskott-Aldridge syndrome
ataxia telangiectasia
Primary defects of phagocytic function: chronic granulomatous disease
leukocyte adhesion deficiency
Complement deficiencies: C1 inhibitor deficiency (hereditary angioedema)
deficiencies of individual complement components
SECONDARY IMMUNODEFICIENCIES: infections (e.g. HIV)
lymphoproliferative diseases (e.g. CLL, multiple myeloma)
causes of reduced production of immune components, e.g. malnutrition, drugs
loss or increased catabolism of immune components e.g. protein losing enteropathy, nephrotic syndrome, burns

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