MicrobiologyBytes: Infection & Immunity Updated: January 7, 2007 Search

Eosinophil.

These cells have the purpose of giving large parasites such as helminths, a hard time. They attach via C3b receptors, the C3b having been produced during the course of alternative pathway complement activation by the helminth. The eosinophils release various substances from their eosinophilic granules. These include major basic protein (MBP), plus cationic proteins, peroxidase, arylsulphatase B, phospholipase D and histaminase. The granule contents are capable of damaging the parasite membrane.

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© AJC 2007.