MicrobiologyBytes: Introduction to Microbiology: Origins of Life Updated: January 19, 2005 Search

The Origins of Life:
Prebiotic Evolution and the Precambrian Fossil Record

Our expanding universe formed around 15 billion years ago (1 billion years is 109 years), in a few seconds from elemental particles in the 'Big Bang'.

Element synthesis up to 56Fe occurs in main sequence stars.

Elements heavier than Fe are synthesized in supernovae:

The solar system and the earth are around 4.6 billion years old.

The oldest rocks on earth date back to 3.8 - 4.0 billion years.

Original atmosphere on earth 'reducing': CO2, N2, H2, CO, H2O + trace amounts of NH3, CH4 (Oparin, Haldane).

Energy input - UV, cosmic rays, radioactivity etc. on the early earth:

The experiments of Stanley Miller:

Abiogenic synthesis of most 'building blocks' e.g. Strecker synthesis:

                                   H2O
 RCHO + HCN + NH3 == RCH (NH2) CN ----->

                    H2O
 RCH (NH2) CO - NH2 ----> RCH (NH2) COOH

Synthesis elsewhere in universe - Hoyle and Wickramasinghe.

Molecules in interstellar space - HCN, HCHO, H2NCN etc.

Problems:

(a) Chirality
(b) Polymerisation
(c) Energy system
The chicken and the egg, which came first? DNA vs. RNA vs. protein.

Ribozymes and the RNA world?

Catalytic function of RNA:

Membrane acquisition:

From the first protobiont to the first prokaryote - when?

The Geological Timetable:

ERA: PERIOD: EPOCH: AGE (millions of years ago): EVENTS:
  Quaternary Recent 0.01 Historic time
Pleistoceine 2.5 Ice ages; humans appear
CENOZOIC Tertiary Pliocene 7 Ape-like ancestors of modern humans
Miocene 25  
Oligocene 38 Origins of most modern mammals
Eocene 54  
Paleocene 65  
MESOZOIC   Cretaceous 135 Flowering plants appear; dinosaurs extinct
Jurassic 190 Conifers, mammals & birds appear; dinosaurs dominant
Triassic 235 Mammal-like reptiles appear
Permian 280 Origin of most modern orders of insects
Carboniferous 345 Origin of reptiles; amphibians & bony fishes dominant; first seed plants
PALEOZOIC   Devonian 395 First land plants
Silurian 450  
Ordovician 500 First vertebrates
Cambrian 570 Origin of most invertebrates
PRECAMBRIAN     4600 Approximate age of the earth

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Fossil discontinuities:

Stanley Tyler and the birth of micropalaentology.

Stromatolites and the stromatolithic cherts.

Major Precambrian fossil sites:

Appearance of oxygen in the atmosphere - red beds.

Completion of element cycles.

Appearance of eukaryotes, 'acritarchs'.

Colonization of land.

HOW DID EUKARYOTES ARISE?

CoverMicrobiology
by L.M.Prescott et al.
A balanced, comprehensive introduction to all major areas of microbiology. The sixth edition has been updated extensively to reflect the latest discoveries in the field.
(Amazon.co.UK)

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