MicrobiologyBytes: Virology: Arboviruses Updated: October 19, 2004 Search

'Arboviruses'

There are a large group (more than 400) of enveloped RNA viruses which are transmitted primarily (but not exclusively) by Arthropod vectors (mosquitoes, sand-flies, fleas, ticks, lice, etc) and which were previously grouped together under the name 'Arboviruses'. More recently, this disordered assemblage has been split into four bona fide virus families:

Family

Genus

Type Species

Hosts

Group IV: (-)sense RNA Viruses

Arenaviridae

Arenavirus

Lymphocytic choriomeningitis virus

Vertebrates

Bunyaviridae

Bunyavirus

Bunyamwera virus

Vertebrates

Hantavirus

Hantaan virus

Vertebrates

Nairovirus

Nairobi sheep disease virus

Vertebrates

Phlebovirus

Sandfly fever Sicilian virus

Vertebrates

Tospovirus

Tomato spotted wilt virus

Plants

Group IV: (+)sense RNA Viruses

Flaviviridae

Flavivirus

Yellow fever virus

Vertebrates

Pestivirus

Bovine diarrhea virus 1

Vertebrates

Hepacivirus

Hepatitis C virus

Vertebrates

Togaviridae

Alphavirus

Sindbis virus

Vertebrates

Rubivirus

Rubella virus

Vertebrates

Mostly, these viruses are relatively fragile (e.g. not resistant to desiccation), therefore many are reliant on vector for transmission. This dependency tends to limit them to tropical & subtropical regions (some exceptions - rubella, HCV). They have complex life-cycles & replicate in both the primary hosts, secondary hosts (which may often be dead-ends) & the Arthropod vectors. Therefore, there may be several animal reservoirs for each virus - eradication would be practically impossible & the best approach is to block transmission by human vaccination/eradication of the vector (e.g. mosquitoes):

Transmission of arboviruses

Many Arboviruses are particularly important in that they are emerging viruses.



© MicrobiologyBytes 2004.